• Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact

The Wright Lab

  • Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact

ClpP inhibitors are produced by a widespread family of bacterial gene clusters →

Authors: Culp EJ, Sychantha D, Hobson C, Pawlowski AC, Prehna G, Wright GD.
Reference: Nat Microbiol.
DOI: 10.1038/s41564-022-01073-4.
PMID: 35246663.

Read more

tags: 2022, Feature, Beth Culp, Dave Sychantha, Christian Hobson, Andrew Pawlowski
Friday 03.04.22
Posted by Gerry Wright
 

Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics →

Authors: Culp EJ, Yim G, Waglechner N, Wang W, Pawlowski AC and Wright GD
Reference: Nat Biotechnol.
DOI: 10.1038/s41587-019-0241-9
PMID: 31501558

Read more

tags: 2019, Beth Culp, Grace Yim, Nicholas Waglechner, Wenliang Wang, Andrew Pawlowski, WAC, Novel Therapeutics
Monday 09.09.19
Posted by Gerry Wright
 

Tri-chlorination of a teicoplanin type glycopeptide antibiotic by the halogenase StaI evades resistance →

Authors: Yim G, Wang W, Pawlowski AC, Wright GD
Reference: Antimicrob Agents Chemother
DOI: 10.1128/AAC.01540-18
PMID: 30275088

Read more

tags: 2018, Grace Yim, Wenliang Wang, Andrew Pawlowski
Monday 10.01.18
Posted by Gerry Wright
 

The evolution of substrate discrimination in macrolide antibiotic resistance enzymes. →

Authors: Pawlowski AC, Stogios PJ, Koteva K, Skarina T, Evdokimova E, Savchenko A, Wright GD
Reference: Nature Communications 2018 ;9(1):112
DOI: 10.1038/s41467-017-02680-0.
PMID: 29317655

Read more

tags: Andrew Pawlowski, Kalinka Koteva, 2018, Feature, Evolution of Resistance
Tuesday 01.09.18
Posted by Wright Lab
 

The complex resistomes of Paenibacillaceae reflect diverse antibiotic chemical ecologies. →

Authors: Pawlowski AC, Westman EL, Koteva K, Waglechner N, Wright GD
Reference: ISME vol 12, 885–897
DOI: 10.1038/s41396-017-0017-5
PMID: 29259290

Read more

tags: Kalinka Koteva, Nicholas Waglechner, Andrew Pawlowski, Antibiotic Resistome, 2017
Tuesday 12.19.17
Posted by Gerry Wright
 

CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database →

Authors: Baofeng Jia, Amogelang R. Raphenya, Brian Alcock, Nicholas Waglechner, Peiyao Guo, Kara K. Tsang, Briony A. Lago, Biren M. Dave, Sheldon Pereira, Arjun N. Sharma, Sachin Doshi, Mélanie Courtot, Raymond Lo, Laura E. Williams, Jonathan G. Frye, Tariq Elsayegh, Daim Sardar, Erin L. Westman, Andrew C. Pawlowski, Timothy A. Johnson, Fiona S.L. Brinkman, Gerard D. Wright and Andrew G. McArthur
Reference: Nucleic Acids Res. 2017 Jan 4;45(D1):D566-D573. doi: 10.1093/nar/gkw1004.
PMID: 27789705

Read more

tags: 2017, Nicholas Waglechner, Andrew Pawlowski
Wednesday 01.04.17
Posted by Gerry Wright
 

Evolving medicinal chemistry strategies in antibiotic discovery →

Authors: AC Pawlowski, JW Johnson, GD Wright
Reference: Curr Opin Biotechnol. 2016 Apr 23;42:108-117. doi: 10.1016/j.copbio.2016.04.006.
PMID: 27116217

Read more

tags: 2016, Andrew Pawlowski, Jarrod Johnson
Saturday 12.31.16
Posted by Wright Lab
 

A diverse intrinsic antibiotic resistome from a cave bacterium →

Authors: Pawlowski AC, Wang W, Koteva K, Barton HA, McArthur AG, Wright GD.
Reference: Nat Commun. 2016 Dec 8;7:13803. doi: 10.1038/ncomms13803.
PMID: 27929110

Read more

tags: 2016, Andrew Pawlowski, Kalinka Koteva, Evolution of Resistance
Thursday 12.08.16
Posted by Wright Lab
 

A Common Platform for Antibiotic Dereplication and Adjuvant Discovery →

Authors: Cox G, Sieron A, King AM, De Pascale G, Pawlowski AC, Koteva K, Wright GD.
Reference: Cell Chem Biol. 2016 Nov 29. pii: S2451-9456(16)30434-2. doi: 10.1016/j.chembiol.2016.11.011.
PMID: 28017602

Read more

tags: 2016, Georgina Cox, Antibiotic Adjuvants, Andrew Pawlowski, Arthur Sieron, Kalinka Koteva, ARP
Tuesday 11.29.16
Posted by Wright Lab
 

The comprehensive antibiotic resistance database →

Authors: Andrew G McArthur, Nicholas Waglechner, Fazmin Nizam, Austin Yan, Marisa A Azad, Alison J Baylay, Kirandeep Bhullar, Marc J Canova, Gianfranco De Pascale, Linda Ejim, Lindsay Kalan, Andrew M King, Kalinka Koteva, Mariya Morar, Michael R Mulvey, Jonathan S O'Brien, Andrew C Pawlowski, Laura JV Piddock, Peter Spanogiannopoulos, Arlene D Sutherland, Irene Tang, Patricia L Taylor, Maulik Thaker, Wenliang Wang, Marie Yan, Tennison Yu, Gerard D Wright
Reference: Antimicrob Agents Chemother. 2013 Jul;57(7):3348-57. doi: 10.1128/AAC.00419-13
PMID: 23650175

Read more

tags: 2013, Andrew Pawlowski, CARD, Nicholas Waglechner, Kalinka Koteva, Linda Ejim, Wenliang Wang
Monday 07.01.13
Posted by Wright Lab
 

Antibiotic resistance is prevalent in an isolated cave microbiome →

Authors: Kirandeep Bhullar, Nicholas Waglechner, Andrew Pawlowski, Kalinka Koteva, Eric D Banks, Michael D Johnston, Hazel A Barton, Gerard D Wright
Reference: PLoS One. 2012;7(4):e34953. doi: 10.1371/journal.pone.0034953.
PMID: 22509370 

Read more

tags: 2012, Kalinka Koteva, Andrew Pawlowski, Nicholas Waglechner
Wednesday 04.11.12
Posted by Wright Lab
 

Copyright © 2021 Wright Lab.
Gallery  |  Links  |  Login  |  Privacy |