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The Wright Lab

  • Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact

2021 Publications

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Featured
Prospects for Antibacterial Discovery and Development
December 22, 2021
Prospects for Antibacterial Discovery and Development
December 22, 2021

Authors: Privalsky TM, Soohoo AM, Wang J, Walsh CT, Wright GD, Gordon EM, Gray NS, Khosla C.
Reference: J Am Chem Soc.
DOI: 10.1021/jacs.1c10200.
PMID: 34860516.

December 22, 2021
Glycopeptide antibiotic discovery in the genomic era
December 21, 2021
Glycopeptide antibiotic discovery in the genomic era
December 21, 2021

Authors: Xu M, Wang W, Wright GD.
Reference: Methods Enzymol.
DOI: 10.1016/bs.mie.2021.11.009. .
PMID: 35379441.

December 21, 2021
Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics
November 2, 2021
Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics
November 2, 2021

Authors: Salamaga B, Kong L, Pasquina-Lemonche L, Lafage L, von Und Zur Muhlen M, Gibson JF, Grybchuk D, Tooke AK, Panchal V, Culp EJ, Tatham E, O'Kane ME, Catley TE, Renshaw SA, Wright GD, Plevka P, Bullough PA, Han A, Hobbs JK, Foster SJ.
Reference: Proc Natl Acad Sci U S A
DOI: 10.1073/pnas.2106022118.
PMID: 34716264.

November 2, 2021
A non-reactive natural product precursor of the duocarmycin family has potent and selective antimalarial activity
October 23, 2021
A non-reactive natural product precursor of the duocarmycin family has potent and selective antimalarial activity
October 23, 2021

Authors: Alder A, Struck NS, Xu M, Johnson JW, Wang W, Pallant D, Cook MA, Rambow J, Lemcke S, Gilberger TW, Wright GD.
Reference: Cell Chem Biol.
DOI: 10.1016/j.chembiol.2021.10.005.
PMID: 34710358.

October 23, 2021
CrpP Is Not a Fluoroquinolone-Inactivating Enzyme
July 16, 2021
CrpP Is Not a Fluoroquinolone-Inactivating Enzyme
July 16, 2021

Authors: Zubyk HL, Wright GD.
Reference: Antimicrob Agents Chemother.
DOI: 10.1128/AAC.00773-21.
PMID: 34001507.

July 16, 2021
Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn2
June 25, 2021
Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn2
June 25, 2021

Authors: Sychantha D, Rotondo CM, Tehrani KHME, Martin NI, Wright GD.
Reference: J Biol Chem.
DOI: 10.1016/j.jbc.2021.100918.
PMID: PMC8319579.

June 25, 2021
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics
May 7, 2021
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics
May 7, 2021

Authors: Benoit YD, Mitchell RR, Wang W, Orlando L, Boyd AL, Tanasijevic B, Aslostovar L, Shapovalova Z, Doyle M, Bergin CJ, Vojnits K, Casado FL, Di Lu J, Porras DP, García-Rodriguez JL, Russell J, Zouggar A, Masibag AN, Caba C, Koteva K, Kinthada LK, Patel JS, Andres SN, Magolan J, Collins TJ, Wright GD, Bhatia M.
Reference: Cell Chem Biol.
DOI: doi: 10.1016/j.chembiol.2021.04.014.
PMID: 33979648.

May 7, 2021
The Enzymes of the Rifamycin Antibiotic Resistome
May 4, 2021
The Enzymes of the Rifamycin Antibiotic Resistome
May 4, 2021

Authors: Surette MD, Spanogiannopoulos P, Wright GD.
Reference: Accounts of Chemical Research
DOI: 10.1021/acs.accounts.1c00048
PMID: 33877820.

May 4, 2021
A Screen of Natural Product Extracts Identifies Moenomycin as a Potent Antigonococcal Agent
April 7, 2021
A Screen of Natural Product Extracts Identifies Moenomycin as a Potent Antigonococcal Agent
April 7, 2021

Authors: Yarlagadda V, Rao VN, Kaur M, Guitor AK, Wright GD.
Reference: ACS Infect Dis.
DOI: doi: 10.1021/acsinfecdis.1c00040.
PMID: 33826296.

April 7, 2021
Ancient Antibiotics, Ancient Resistance
March 9, 2021
Ancient Antibiotics, Ancient Resistance
March 9, 2021

Authors: Waglechner N, Culp EJ, Wright GD.
Reference: EcoSal Plus.
DOI: doi: 10.1128/ecosalplus.ESP-0027-2020.
PMID: 33734062.

March 9, 2021
 

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