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The Wright Lab

  • Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact

2021 Publications

Featured | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 1998-2009

Featured
Prospects for Antibacterial Discovery and Development
Dec 22, 2021
Prospects for Antibacterial Discovery and Development
Dec 22, 2021

Authors: Privalsky TM, Soohoo AM, Wang J, Walsh CT, Wright GD, Gordon EM, Gray NS, Khosla C.
Reference: J Am Chem Soc.
DOI: 10.1021/jacs.1c10200.
PMID: 34860516.

Dec 22, 2021
Glycopeptide antibiotic discovery in the genomic era
Dec 21, 2021
Glycopeptide antibiotic discovery in the genomic era
Dec 21, 2021

Authors: Xu M, Wang W, Wright GD.
Reference: Methods Enzymol.
DOI: 10.1016/bs.mie.2021.11.009. .
PMID: 35379441.

Dec 21, 2021
Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics
Nov 2, 2021
Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics
Nov 2, 2021

Authors: Salamaga B, Kong L, Pasquina-Lemonche L, Lafage L, von Und Zur Muhlen M, Gibson JF, Grybchuk D, Tooke AK, Panchal V, Culp EJ, Tatham E, O'Kane ME, Catley TE, Renshaw SA, Wright GD, Plevka P, Bullough PA, Han A, Hobbs JK, Foster SJ.
Reference: Proc Natl Acad Sci U S A
DOI: 10.1073/pnas.2106022118.
PMID: 34716264.

Nov 2, 2021
A non-reactive natural product precursor of the duocarmycin family has potent and selective antimalarial activity
Oct 23, 2021
A non-reactive natural product precursor of the duocarmycin family has potent and selective antimalarial activity
Oct 23, 2021

Authors: Alder A, Struck NS, Xu M, Johnson JW, Wang W, Pallant D, Cook MA, Rambow J, Lemcke S, Gilberger TW, Wright GD.
Reference: Cell Chem Biol.
DOI: 10.1016/j.chembiol.2021.10.005.
PMID: 34710358.

Oct 23, 2021
CrpP Is Not a Fluoroquinolone-Inactivating Enzyme
Jul 16, 2021
CrpP Is Not a Fluoroquinolone-Inactivating Enzyme
Jul 16, 2021

Authors: Zubyk HL, Wright GD.
Reference: Antimicrob Agents Chemother.
DOI: 10.1128/AAC.00773-21.
PMID: 34001507.

Jul 16, 2021
Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn2
Jun 25, 2021
Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn2
Jun 25, 2021

Authors: Sychantha D, Rotondo CM, Tehrani KHME, Martin NI, Wright GD.
Reference: J Biol Chem.
DOI: 10.1016/j.jbc.2021.100918.
PMID: PMC8319579.

Jun 25, 2021
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics
May 7, 2021
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics
May 7, 2021

Authors: Benoit YD, Mitchell RR, Wang W, Orlando L, Boyd AL, Tanasijevic B, Aslostovar L, Shapovalova Z, Doyle M, Bergin CJ, Vojnits K, Casado FL, Di Lu J, Porras DP, García-Rodriguez JL, Russell J, Zouggar A, Masibag AN, Caba C, Koteva K, Kinthada LK, Patel JS, Andres SN, Magolan J, Collins TJ, Wright GD, Bhatia M.
Reference: Cell Chem Biol.
DOI: doi: 10.1016/j.chembiol.2021.04.014.
PMID: 33979648.

May 7, 2021
The Enzymes of the Rifamycin Antibiotic Resistome
May 4, 2021
The Enzymes of the Rifamycin Antibiotic Resistome
May 4, 2021

Authors: Surette MD, Spanogiannopoulos P, Wright GD.
Reference: Accounts of Chemical Research
DOI: 10.1021/acs.accounts.1c00048
PMID: 33877820.

May 4, 2021
A Screen of Natural Product Extracts Identifies Moenomycin as a Potent Antigonococcal Agent
Apr 7, 2021
A Screen of Natural Product Extracts Identifies Moenomycin as a Potent Antigonococcal Agent
Apr 7, 2021

Authors: Yarlagadda V, Rao VN, Kaur M, Guitor AK, Wright GD.
Reference: ACS Infect Dis.
DOI: doi: 10.1021/acsinfecdis.1c00040.
PMID: 33826296.

Apr 7, 2021
Ancient Antibiotics, Ancient Resistance
Mar 9, 2021
Ancient Antibiotics, Ancient Resistance
Mar 9, 2021

Authors: Waglechner N, Culp EJ, Wright GD.
Reference: EcoSal Plus.
DOI: doi: 10.1128/ecosalplus.ESP-0027-2020.
PMID: 33734062.

Mar 9, 2021
 

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