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The Wright Lab

  • Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact

2010 Publications

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Featured
Dec 1, 2010
The genomic enzymology of antibiotic resistance
Dec 1, 2010

Authors: Mariya Morar, Gerard D Wright
Reference: Annu Rev Genet. 2010;44:25-51. doi: 10.1146/annurev-genet-102209-163517.
PMID: 20822442

Dec 1, 2010
Oct 31, 2010
Antibiotic resistance in the environment: a link to the clinic?
Oct 31, 2010

Authors: Gerard D Wright
Reference: Curr Opin Microbiol. 2010 Oct;13(5):589-94. doi: 10.1016/j.mib.2010.08.005.
PMID: 20850375

Oct 31, 2010
Sep 24, 2010
Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: a model for the ClpX/ClpA-bound state of ClpP
Sep 24, 2010

Authors: Dominic Him Shun Li, Yu Seon Chung, Melanie Gloyd, Ebenezer Joseph, Rodolfo Ghirlando, Gerard D Wright, Yi-Qiang Cheng, Michael R Maurizi, Alba Guarné, Joaquin Ortega
Reference: Chem Biol. 2010 Sep 24;17(9):959-69. doi: 10.1016/j.chembiol.2010.07.008.
PMID: 20851345 

Sep 24, 2010
Sep 20, 2010
Q&A: Antibiotic resistance: where does it come from and what can we do about it?
Sep 20, 2010

Authors: Gerard D Wright
Reference: BMC Biol. 2010 Sep 20;8:123. doi: 10.1186/1741-7007-8-123.
PMID: 20887638 

Sep 20, 2010
Aug 1, 2010
The antibiotic resistome
Aug 1, 2010

Authors: Gerard D Wright
Reference: Expert Opin Drug Discov. 2010 Aug;5(8):779-88. doi: 10.1517/17460441.2010.497535. 
PMID: 22827799

Aug 1, 2010
Jul 5, 2010
Antibiotic resistance by enzyme inactivation: from mechanisms to solutions
Jul 5, 2010

Authors: Gianfranco De Pascale, Gerard D Wright
Reference: Chembiochem. 2010 Jul 5;11(10):1325-34. doi: 10.1002/cbic.201000067.
PMID: 20564281 

Jul 5, 2010
May 1, 2010
A vancomycin photoprobe identifies the histidine kinase VanSsc as a vancomycin receptor
May 1, 2010

Authors: Kalinka Koteva, Hee-Jeon Hong, Xiao Dong Wang, Ishac Nazi, Donald Hughes, Mike J Naldrett, Mark J Buttner, Gerard D Wright
Reference: Nat Chem Biol. 2010 May;6(5):327-9. doi: 10.1038/nchembio.350.
PMID: 20383152 

May 1, 2010
May 1, 2010
Nucleotide selectivity of antibiotic kinases
May 1, 2010

Authors: Tushar Shakya, Gerard D Wright
Reference: Antimicrob Agents Chemother. 2010 May;54(5):1909-13. doi: 10.1128/AAC.01570-09
PMID: 20231391

May 1, 2010
May 1, 2010
Crystallization and preliminary X-ray crystallographic analysis of the tetracycline-degrading monooxygenase TetX2 from Bacteroides thetaiotaomicron
May 1, 2010

Authors: Gesa Volkers, Linda Schuldt, Gottfried J Palm, Gerard D Wright, Winfried Hinrichs
Reference: Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt 5):611-4. doi: 10.1107/S174430911001225X.
PMID: 20445272 

May 1, 2010
Apr 1, 2010
Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1
Apr 1, 2010

Authors: Nancy L McKenzie, Maulik Thaker, Kalinka Koteva, Donald W Hughes, Gerard D Wright, Justin R Nodwell
Reference: J Antibiot (Tokyo). 2010 Apr;63(4):177-82. doi: 10.1038/ja.2010.13. 
PMID: 20224601 

Apr 1, 2010
Feb 2, 2010
Antibiotics: inactive but not inert
Feb 2, 2010

Authors: Gerard D Wright
Reference: Nat Chem Biol. 2010 Feb;6(2):85-6. doi: 10.1038/nchembio.299.
PMID: 20081820

Feb 2, 2010
Feb 1, 2010
The tetracycline resistome
Feb 1, 2010

Authors: Maulik Thaker, Peter Spanogiannopoulos, Gerard D Wright
Reference: Cell Mol Life Sci. 2010 Feb;67(3):419-31. doi: 10.1007/s00018-009-0172-6. 
PMID: 19862477

Feb 1, 2010
Jan 14, 2010
Structural and kinetic characterization of the LPS biosynthetic enzyme d-α, β-d-heptose-1, 7-bisphosphate phosphatase (GmhB) from Escherichia coli
Jan 14, 2010

Authors: Patricia L Taylor, Seiji Sugiman-Marangos, Kun Zhang, Miguel A Valvano, Gerard D Wright, Murray S Junop
Reference: Biochemistry. 2010 Feb 9;49(5):1033-41. doi: 10.1021/bi901780j.
PMID: 20050699 

Jan 14, 2010

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