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The Wright Lab

  • Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact

2014 Publications

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Featured
Forces shaping the antibiotic resistome
Dec 1, 2014
Forces shaping the antibiotic resistome
Dec 1, 2014

Authors: Julie A Perry, Gerard D Wright
Reference: Bioessays. 2014 Dec;36(12):1179-84. doi: 10.1002/bies.201400128.
PMID: 25213620

Dec 1, 2014
Harnessing the Synthetic Capabilities of Glycopeptide Antibiotic Tailoring Enzymes: Characterization of the UK‐68,597 Biosynthetic Cluster
Nov 24, 2014
Harnessing the Synthetic Capabilities of Glycopeptide Antibiotic Tailoring Enzymes: Characterization of the UK‐68,597 Biosynthetic Cluster
Nov 24, 2014

Authors: Grace Yim, Lindsay Kalan, Kalinka Koteva, Maulik N Thaker, Nicholas Waglechner, Irene Tang, Gerard D Wright
Reference: Chembiochem. 2014 Nov 24;15(17):2613-23. doi: 10.1002/cbic.201402179. 
PMID: 25255985 

Nov 24, 2014
Role of PBPD1 in Stimulation of Listeria monocytogenes Biofilm Formation by Subminimal Inhibitory β-Lactam Concentrations
Nov 1, 2014
Role of PBPD1 in Stimulation of Listeria monocytogenes Biofilm Formation by Subminimal Inhibitory β-Lactam Concentrations
Nov 1, 2014

Authors: Uyen T Nguyen, Hanjeong Harvey, Andrew J Hogan, Alexandria CF Afonso, Gerard D Wright, Lori L Burrows
Reference: Antimicrob Agents Chemother. 2014 Nov;58(11):6508-17. doi: 10.1128/AAC.03671-14. 
PMID: 25136010 

Nov 1, 2014
Inhibition of the ANT (2 ″)-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones
Nov 1, 2014
Inhibition of the ANT (2 ″)-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones
Nov 1, 2014

Authors: Danielle R Hirsch, Georgina Cox, Michael P D’Erasmo, Tushar Shakya, Christine Meck, Noushad Mohd, Gerard D Wright, Ryan P Murelli
Reference: Bioorg Med Chem Lett. 2014 Nov 1;24(21):4943-7. doi: 10.1016/j.bmcl.2014.09.037.
PMID: 25283553 

Nov 1, 2014
The antibiotic resistome: what's new?
Oct 31, 2014
The antibiotic resistome: what's new?
Oct 31, 2014

Authors: Julie Ann Perry, Erin Louise Westman, Gerard D Wright
Reference: Curr Opin Microbiol. 2014 Oct;21:45-50. doi: 10.1016/j.mib.2014.09.002. 
PMID: 25280222

Oct 31, 2014
A macrophage-stimulating compound from a screen of microbial natural products
Jul 2, 2014
A macrophage-stimulating compound from a screen of microbial natural products
Jul 2, 2014

Authors: Perry JA, Koteva K, Verschoor CP, Wang W, Bowdish DM, Wright GD.
Reference: J Antibiot (Tokyo). 2015 Jan;68(1):40-6. doi: 10.1038/ja.2014.83.
PMID: 24984798

Jul 2, 2014
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance.
Jun 26, 2014
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance.
Jun 26, 2014

Authors: Andrew M King, Sarah A Reid-Yu, Wenliang Wang, Dustin T King, Gianfranco De Pascale, Natalie C Strynadka, Timothy R Walsh, Brian K Coombes, Gerard D Wright
Reference: Nature. 2014 Jun 26;510(7506):503-6. doi: 10.1038/nature13445.
PMID: 24965651

Jun 26, 2014
Antibiotic resistance–mediated isolation of scaffold-specific natural product producers
May 29, 2014
Antibiotic resistance–mediated isolation of scaffold-specific natural product producers
May 29, 2014

Authors:  Maulik N Thaker, Nicholas Waglechner and Gerry D Wright
Reference: Nature Protocols 9, 1469–1479 (2014) doi:10.1038/nprot.2014.093
PMID: 24874813

May 29, 2014
A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria
May 13, 2014
A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria
May 13, 2014

Authors: Peter Spanogiannopoulos, Nicholas Waglechner, Kalinka Koteva, Gerard D Wright
Reference: Proc Natl Acad Sci U S A. 2014 May 13;111(19):7102-7. doi: 10.1073/pnas.1402358111
PMID: 24778229 

May 13, 2014
May 1, 2014
Perspective: synthetic biology revives antibiotics
May 1, 2014

Authors: Gerard Wright
Reference: Nature. 2014 May 1;509(7498):S13. doi: 10.1038/509S13a.
PMID: 24784423 

May 1, 2014
May 1, 2014
Winners of the 2013 JA Medals for excellence
May 1, 2014

Authors: Gerard D Wright, Minoru Yoshida
Reference: J Antibiot (Tokyo). 2014 May;67(5):351-2. doi: 10.1038/ja.2014.29.
PMID: 24862629

May 1, 2014
An unusual class of anthracyclines potentiate Gram-positive antibiotics in intrinsically resistant Gram-negative bacteria
Mar 13, 2014
An unusual class of anthracyclines potentiate Gram-positive antibiotics in intrinsically resistant Gram-negative bacteria
Mar 13, 2014

Authors: Georgina Cox, Kalinka Koteva, Gerard D Wright
Reference: J Antimicrob Chemother. 2014 Jul;69(7):1844-55. doi: 10.1093/jac/dku057.
PMID: 24627312 

Mar 13, 2014
Feb 27, 2014
Draft genome sequence of the sulfonamide antibiotic-degrading Microbacterium sp. strain C448
Feb 27, 2014

Authors: Fabrice Martin-Laurent, Romain Marti, Nicholas Waglechner, Gerard D Wright, Edward Topp
Reference: Genome Announc. 2014 Feb 13;2(1). pii: e01113-13. doi: 10.1128/genomeA.01113-13.
PMID: 24526651 

Feb 27, 2014
Feb 1, 2014
Designing analogs of ticlopidine, a wall teichoic acid inhibitor, to avoid formation of its oxidative metabolites
Feb 1, 2014

Authors: Maya A Farha, Kalinka Koteva, Robert T Gale, Edward W Sewell, Gerard D Wright, Eric D Brown
Reference: Bioorg Med Chem Lett. 2014 Feb 1;24(3):905-10. doi: 10.1016/j.bmcl.2013.12.069.
PMID: 24393581 

Feb 1, 2014
Jan 22, 2014
Something old, something new: revisiting natural products in antibiotic drug discovery
Jan 22, 2014

Authors: Gerard D Wright
Reference: Can J Microbiol. 2014 Mar;60(3):147-54. doi: 10.1139/cjm-2014-0063. 
PMID: 24588388 

Jan 22, 2014
Jan 16, 2014
Metal-induced isomerization yields an intracellular chelator that disrupts bacterial iron homeostasis
Jan 16, 2014

Authors: Shannon B Falconer, Wenliang Wang, Sebastian S Gehrke, Jessica D Cuneo, James F Britten, Gerard D Wright, Eric D Brown
Reference: Chem Biol. 2014 Jan 16;21(1):136-45. doi: 10.1016/j.chembiol.2013.11.007
PMID: 24361049

Jan 16, 2014
Jan 1, 2014
Glycopeptide antibiotic biosynthesis
Jan 1, 2014

Authors: Grace Yim, Maulik N Thaker, Kalinka Koteva, Gerard Wright
Reference: J Antibiot (Tokyo). 2014 Jan;67(1):31-41. doi: 10.1038/ja.2013.117.
PMID: 24220108

Jan 1, 2014
Jan 1, 2014
Christopher Walsh: Pioneer and innovator in antibiotic and natural product chemical biology
Jan 1, 2014

Authors: Gerard D Wright
Reference: J Antibiot (Tokyo). 2014 Jan;67(1):5-6. doi: 10.1038/ja.2013.118.
PMID: 24463296

Jan 1, 2014

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