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The Wright Lab

  • Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact

2020 Publications

Featured | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 1998-2009

 
Featured
Resistance-Guided Discovery of Elfamycin Antibiotic Producers with Antigonococcal Activity
Nov 7, 2020
Resistance-Guided Discovery of Elfamycin Antibiotic Producers with Antigonococcal Activity
Nov 7, 2020

Authors: Yarlagadda V, Medina R, Johnson TA, Koteva KP, Cox G, Thaker MN, Wright GD.
Reference: ACS Infect Dis.
DOI: 10.1021/acsinfecdis.0c00467
PMID: 33164482

Nov 7, 2020
GPAHex-A synthetic biology platform for Type IV-V glycopeptide antibiotic production and discovery
Oct 16, 2020
GPAHex-A synthetic biology platform for Type IV-V glycopeptide antibiotic production and discovery
Oct 16, 2020

Authors: Xu M, Wang W, Waglechner N, Culp EJ, Guitor AK, Wright GD.
Reference: Nat Commun.
DOI: 10.1038/s41467-020-19138-5
PMID: 33067466

Oct 16, 2020
Membrane interactions of non-membrane targeting antibiotics: The case of aminoglycosides, macrolides, and fluoroquinolones
Aug 21, 2020
Membrane interactions of non-membrane targeting antibiotics: The case of aminoglycosides, macrolides, and fluoroquinolones
Aug 21, 2020

Authors: Khondker A, Bider RC, Passos-Gastaldo I, Wright GD, Rheinstädter MC.
Reference: Biochim Biophys Acta Biomembr.
DOI: 0.1016/j.bbamem.2020.183448
PMID: 32828850

Aug 21, 2020
Jun 16, 2020
COVID-19 and Antimicrobial Resistance: Parallel and Interacting Health Emergencies
Jun 16, 2020

Authors: Nieuwlaat R, Mbuagbaw L, Mertz D, Burrows L, Bowdish DME, Moja L, Wright GD, Schünemann HJ.
Reference: Clin Infect Dis.
DOI: 110.1093/cid/ciaa773
PMID: 32544232

Jun 16, 2020
Antibiotic Resistance by Enzymatic Modification of Antibiotic Targets
Jun 1, 2020
Antibiotic Resistance by Enzymatic Modification of Antibiotic Targets
Jun 1, 2020

Authors: Schaenzer AJ and Wright GD
Reference: Trends Mol Med.
DOI: 10.1016/j.molmed.2020.05.001
PMID: 32493628

Jun 1, 2020
Venturicidin A, A Membrane-active Natural Product Inhibitor of ATP synthase Potentiates Aminoglycoside Antibiotics
May 18, 2020
Venturicidin A, A Membrane-active Natural Product Inhibitor of ATP synthase Potentiates Aminoglycoside Antibiotics
May 18, 2020

Authors: Yarlagadda V, Medina R and Wright GD
Reference: Sci Rep.
DOI: 10.1038/s41598-020-64756-0
PMID: 32424122

May 18, 2020
Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development
Feb 24, 2020
Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development
Feb 24, 2020

Authors: Jacques S, van der Sloot AM, Huard CC, Coulombe-Huntington J, Tsao S, Tollis S, Bertomeu T, Culp EJ, Pallant D, Cook MA, Bonneil E, Thibault P, Wright GD and Tyers M.
Reference: Genetics
DOI: 10.1534/genetics.119.302851
PMID: 32094149

Feb 24, 2020
Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling
Feb 12, 2020
Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling
Feb 12, 2020

Authors: Culp EJ, Waglecher N, Wang W, Fiebig-Comyn AA, Hsu Y, Koteva K, Sychantha D, Coombes BK, Van Nieuwenhze MS, Brun YV and Wright GD
Reference: Nature
DOI: 10.1038/s41586-020-1990-9
PMID: 32051588

Feb 12, 2020
Suppression of β-Lactam Resistance by Aspergillomarasmine A Is Influenced by both the Metallo-β-Lactamase Target and the Antibiotic Partner
Jan 14, 2020
Suppression of β-Lactam Resistance by Aspergillomarasmine A Is Influenced by both the Metallo-β-Lactamase Target and the Antibiotic Partner
Jan 14, 2020

Authors: Rotondo CM, Sychantha D, Koteva K and Wright GD
Reference: Antimicrob Agents Chemother.
DOI: 10.1128/AAC.01386-19
PMID: 31932375

Jan 14, 2020
CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database
Jan 8, 2020
CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database
Jan 8, 2020

Authors: Alcock BP, Raphenya AR, Lau TTY, Tsang KK, Bouchard M, Edalatmand A, Huynh W, Nguyen AV, Cheng AA, Liu S, Min SY, Miroshnichenko A, Tran HK, Werfalli RE, Nasir JA, Oloni M, Speicher DJ, Florescu A, Singh B, Faltyn M, Hernandez-Koutoucheva A, Sharma AN, Bordeleau E, Pawlowski AC, Zubyk HL, Dooley D, Griffiths E, Maguire F, Winsor GL, Beiko RG, Brinkman FSL, Hsiao WWL, Domselaar GV, McArthur AG.
Reference: Nucleic Acids Res.
DOI: 10.1093/nar/gkz935
PMID: 31665441

Jan 8, 2020

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