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The Wright Lab

  • Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact

2017 Publications

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Featured
The complex resistomes of Paenibacillaceae reflect diverse antibiotic chemical ecologies.
Dec 19, 2017
The complex resistomes of Paenibacillaceae reflect diverse antibiotic chemical ecologies.
Dec 19, 2017

Authors: Pawlowski AC, Westman EL, Koteva K, Waglechner N, Wright GD
Reference: ISME vol 12, 885–897
DOI: 10.1038/s41396-017-0017-5
PMID: 29259290

Dec 19, 2017
Transformation of the anticancer drug doxorubicin in the human gut microbiome
Nov 21, 2017
Transformation of the anticancer drug doxorubicin in the human gut microbiome
Nov 21, 2017

Authors: A Yan, E Culp, J Perry, J Lau, L MacNeil, MG Surette, GD Wright
Reference: ACS Infectious Disease (Available online November 21 2017) 
DOI: 10.1021/acsinfecdis.7b00166
PMID: 29160065

Nov 21, 2017
Inhibitors of metallo-β-lactamases.
Nov 16, 2017
Inhibitors of metallo-β-lactamases.
Nov 16, 2017

Authors: CM Rotondo and GD Wright
Reference: Current Opinion in Microbiology 2017 39: 96-105
PMID: 29154026

Nov 16, 2017
Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7.
Nov 9, 2017
Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7.
Nov 9, 2017

Authors: Bergstrom A, Katko A, Adkins Z, Hill J, Cheng Z, Burnett M, Yang H, Aitha M, Mehaffey MR, Brodbelt JS, Tehrani KHME, Martin NI, Bonomo RA, Page RC, Tierney DL, Fast W, Wright GD, Crowder MW
Reference: ACS Infectious Disease (Epub)
DOI: 10.1021/acsinfecdis.7b00106
PMID: 29091730

Nov 9, 2017
Exploiting the Sensitivity of Nutrient Transporter Deletion Strains in Discovery of Natural Product Antimetabolites.
Oct 25, 2017
Exploiting the Sensitivity of Nutrient Transporter Deletion Strains in Discovery of Natural Product Antimetabolites.
Oct 25, 2017

Authors: Gehrke SS, Kumar G, Yokubynas NA, Côté JP, Wang W, French S, MacNair CR, Wright GD, Brown ED.
Reference: ACS Infectious Disease (Epub) 
DOI: 10.1021/acsinfecdis.7b00149
PMID: 29069544

Oct 25, 2017
Lessons from Environmental Antibiotic Resistome
Sep 28, 2017
Lessons from Environmental Antibiotic Resistome
Sep 28, 2017

Authors: MD Surette and GD Wright
Reference: Annual Review of Microbiology Vol. 71:309-329
PMID: 28657887

Sep 28, 2017
Antibiotic resistance: it’s bad, but why isn’t it worse?
Sep 15, 2017
Antibiotic resistance: it’s bad, but why isn’t it worse?
Sep 15, 2017

Authors: N Waglechner and GD Wright
Reference: BMC Biology. 2017 Sep 15;15:84. doi.org/10.1186/s12915-017-0423-1
PMID: 28915805

Sep 15, 2017
Pharmacodynamics of dose-escalated 'front-loading' polymyxin B regimens against polymyxin-resistant mcr-1-harbouring Escherichia coli.
Aug 1, 2017
Pharmacodynamics of dose-escalated 'front-loading' polymyxin B regimens against polymyxin-resistant mcr-1-harbouring Escherichia coli.
Aug 1, 2017

Authors: Smith NM, Bulman ZP, Sieron AO, Bulitta JB, Holden PN, Nation RL, Li J, Wright GD, Tsuji BT. 
Reference: Journal of Antimicrobial Chemotherapy 2017 Aug 1;72(8):2297-2303
PMID: 28505268

Aug 1, 2017
Opportunities for natural products in 21st century antibiotic discovery.
Jul 1, 2017
Opportunities for natural products in 21st century antibiotic discovery.
Jul 1, 2017

Author: GD Wright
Reference: Natural Products Reports 2017, 34, 694-701
PMID: 28569300

Jul 1, 2017
CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database
Jan 4, 2017
CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database
Jan 4, 2017

Authors: Baofeng Jia, Amogelang R. Raphenya, Brian Alcock, Nicholas Waglechner, Peiyao Guo, Kara K. Tsang, Briony A. Lago, Biren M. Dave, Sheldon Pereira, Arjun N. Sharma, Sachin Doshi, Mélanie Courtot, Raymond Lo, Laura E. Williams, Jonathan G. Frye, Tariq Elsayegh, Daim Sardar, Erin L. Westman, Andrew C. Pawlowski, Timothy A. Johnson, Fiona S.L. Brinkman, Gerard D. Wright and Andrew G. McArthur
Reference: Nucleic Acids Res. 2017 Jan 4;45(D1):D566-D573. doi: 10.1093/nar/gkw1004.
PMID: 27789705

Jan 4, 2017

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