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The Wright Lab

  • Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact

2018 Publications

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Featured
December 19, 2018
Unlocking the Potential of Natural Products in Drug Discovery
December 19, 2018

Authors: Wright GD
Reference: Microb. Biotechnol.
DOI: 10.1111/1751-7915.13351
PMID: 30565871

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December 19, 2018
Heterologous expression-facilitated natural products’ discovery in actinomycetes
November 16, 2018
Heterologous expression-facilitated natural products’ discovery in actinomycetes
November 16, 2018

Authors: Xu M, Wright GD
Reference: J Ind Microbiol Biotechnol.
DOI: 10.1007/s10295-018-2097-2
PMID: 30446891

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November 16, 2018
Antimicrobial Resistance and Respiratory Infections
November 1, 2018
Antimicrobial Resistance and Respiratory Infections
November 1, 2018

Authors: Guitor AK, Wright GD
Reference: Chest
DOI: 10.1016/j.chest.2018.06.019
PMID: 29959904

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November 1, 2018
Tri-chlorination of a teicoplanin type glycopeptide antibiotic by the halogenase StaI evades resistance
October 1, 2018
Tri-chlorination of a teicoplanin type glycopeptide antibiotic by the halogenase StaI evades resistance
October 1, 2018

Authors: Yim G, Wang W, Pawlowski AC, Wright GD
Reference: Antimicrob Agents Chemother
DOI: 10.1128/AAC.01540-18
PMID: 30275088

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October 1, 2018
Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes
June 4, 2018
Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes
June 4, 2018

Authors: Cox G, Ejim L, Stogios PJ, Koteva K, Bordeleau E, Sieron AO, Savchenko A, Serio AW, Krause KM, Wright GD
Reference: ACS Infectious Diseases 2018
DOI: 10.1021/acsinfecdis.8b00001
PMID: 29634241

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June 4, 2018
Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis
June 4, 2018
Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis
June 4, 2018

Authors: Stogios PJ, Cox G, Zubyk HL, Evdokimova E, Wawrzak Z, Wright GD, Savchenko A
Reference: 
ACS Chemical Biology 2018 13 (5), 1322-1332
DOI: 
10.1021/acschembio.8b00116
PMID: 
29631403

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June 4, 2018
Rox, a Rifamycin Resistance Enzyme with an Unprecedented Mechanism of Action.
February 1, 2018
Rox, a Rifamycin Resistance Enzyme with an Unprecedented Mechanism of Action.
February 1, 2018

Authors: Koteva K, Cox G, Kelso JK, Surette MD, Zubyk HL, Ejim L, Stogios P, Savchenko A, Sørensen, Wright GD
Reference: Cell Chemical Biology 2018 Jan 26. pii: S2451-9456(18)30031-X
DOI: 10.1016/j.chembiol.2018.01.009.
PMID: 29398560

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February 1, 2018
The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
January 9, 2018
The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
January 9, 2018

Authors: Pawlowski AC, Stogios PJ, Koteva K, Skarina T, Evdokimova E, Savchenko A, Wright GD
Reference: Nature Communications 2018 ;9(1):112
DOI: 10.1038/s41467-017-02680-0.
PMID: 29317655

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January 9, 2018

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