Authors: Julie A Perry, Gerard D Wright
Reference: Bioessays. 2014 Dec;36(12):1179-84. doi: 10.1002/bies.201400128.
PMID: 25213620
Harnessing the Synthetic Capabilities of Glycopeptide Antibiotic Tailoring Enzymes: Characterization of the UK‐68,597 Biosynthetic Cluster →
Authors: Grace Yim, Lindsay Kalan, Kalinka Koteva, Maulik N Thaker, Nicholas Waglechner, Irene Tang, Gerard D Wright
Reference: Chembiochem. 2014 Nov 24;15(17):2613-23. doi: 10.1002/cbic.201402179.
PMID: 25255985
Role of PBPD1 in Stimulation of Listeria monocytogenes Biofilm Formation by Subminimal Inhibitory β-Lactam Concentrations →
Authors: Uyen T Nguyen, Hanjeong Harvey, Andrew J Hogan, Alexandria CF Afonso, Gerard D Wright, Lori L Burrows
Reference: Antimicrob Agents Chemother. 2014 Nov;58(11):6508-17. doi: 10.1128/AAC.03671-14.
PMID: 25136010
Inhibition of the ANT (2 ″)-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic α-hydroxytropolones →
Authors: Danielle R Hirsch, Georgina Cox, Michael P D’Erasmo, Tushar Shakya, Christine Meck, Noushad Mohd, Gerard D Wright, Ryan P Murelli
Reference: Bioorg Med Chem Lett. 2014 Nov 1;24(21):4943-7. doi: 10.1016/j.bmcl.2014.09.037.
PMID: 25283553
The antibiotic resistome: what's new? →
Authors: Julie Ann Perry, Erin Louise Westman, Gerard D Wright
Reference: Curr Opin Microbiol. 2014 Oct;21:45-50. doi: 10.1016/j.mib.2014.09.002.
PMID: 25280222
A macrophage-stimulating compound from a screen of microbial natural products →
Authors: Perry JA, Koteva K, Verschoor CP, Wang W, Bowdish DM, Wright GD.
Reference: J Antibiot (Tokyo). 2015 Jan;68(1):40-6. doi: 10.1038/ja.2014.83.
PMID: 24984798
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance. →
Authors: Andrew M King, Sarah A Reid-Yu, Wenliang Wang, Dustin T King, Gianfranco De Pascale, Natalie C Strynadka, Timothy R Walsh, Brian K Coombes, Gerard D Wright
Reference: Nature. 2014 Jun 26;510(7506):503-6. doi: 10.1038/nature13445.
PMID: 24965651
Antibiotic resistance–mediated isolation of scaffold-specific natural product producers →
Authors: Maulik N Thaker, Nicholas Waglechner and Gerry D Wright
Reference: Nature Protocols 9, 1469–1479 (2014) doi:10.1038/nprot.2014.093
PMID: 24874813
A rifamycin inactivating phosphotransferase family shared by environmental and pathogenic bacteria →
Authors: Peter Spanogiannopoulos, Nicholas Waglechner, Kalinka Koteva, Gerard D Wright
Reference: Proc Natl Acad Sci U S A. 2014 May 13;111(19):7102-7. doi: 10.1073/pnas.1402358111
PMID: 24778229
Perspective: synthetic biology revives antibiotics →
Authors: Gerard Wright
Reference: Nature. 2014 May 1;509(7498):S13. doi: 10.1038/509S13a.
PMID: 24784423
Winners of the 2013 JA Medals for excellence →
Authors: Gerard D Wright, Minoru Yoshida
Reference: J Antibiot (Tokyo). 2014 May;67(5):351-2. doi: 10.1038/ja.2014.29.
PMID: 24862629
An unusual class of anthracyclines potentiate Gram-positive antibiotics in intrinsically resistant Gram-negative bacteria →
Authors: Georgina Cox, Kalinka Koteva, Gerard D Wright
Reference: J Antimicrob Chemother. 2014 Jul;69(7):1844-55. doi: 10.1093/jac/dku057.
PMID: 24627312
Draft genome sequence of the sulfonamide antibiotic-degrading Microbacterium sp. strain C448 →
Authors: Fabrice Martin-Laurent, Romain Marti, Nicholas Waglechner, Gerard D Wright, Edward Topp
Reference: Genome Announc. 2014 Feb 13;2(1). pii: e01113-13. doi: 10.1128/genomeA.01113-13.
PMID: 24526651
Designing analogs of ticlopidine, a wall teichoic acid inhibitor, to avoid formation of its oxidative metabolites →
Authors: Maya A Farha, Kalinka Koteva, Robert T Gale, Edward W Sewell, Gerard D Wright, Eric D Brown
Reference: Bioorg Med Chem Lett. 2014 Feb 1;24(3):905-10. doi: 10.1016/j.bmcl.2013.12.069.
PMID: 24393581
Something old, something new: revisiting natural products in antibiotic drug discovery →
Authors: Gerard D Wright
Reference: Can J Microbiol. 2014 Mar;60(3):147-54. doi: 10.1139/cjm-2014-0063.
PMID: 24588388
Metal-induced isomerization yields an intracellular chelator that disrupts bacterial iron homeostasis →
Authors: Shannon B Falconer, Wenliang Wang, Sebastian S Gehrke, Jessica D Cuneo, James F Britten, Gerard D Wright, Eric D Brown
Reference: Chem Biol. 2014 Jan 16;21(1):136-45. doi: 10.1016/j.chembiol.2013.11.007
PMID: 24361049
Glycopeptide antibiotic biosynthesis →
Authors: Grace Yim, Maulik N Thaker, Kalinka Koteva, Gerard Wright
Reference: J Antibiot (Tokyo). 2014 Jan;67(1):31-41. doi: 10.1038/ja.2013.117.
PMID: 24220108
Christopher Walsh: Pioneer and innovator in antibiotic and natural product chemical biology →
Authors: Gerard D Wright
Reference: J Antibiot (Tokyo). 2014 Jan;67(1):5-6. doi: 10.1038/ja.2013.118.
PMID: 24463296