Authors: Surette MD, Waglechner N, Koteva K, Wright GD.
Reference: Mol Cell.
DOI: 10.1016/j.molcel.2022.06.019.
PMID: 35907401
Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family →
Authors: Stogios PJ, Bordeleau E, Xu Z, Skarina T, Evdokimova E, Chou S, Diorio-Toth L, D'Souza AW, Patel S, Dantas G, Wright GD, Savchenko A.
Reference: Commun Biol.
DOI: 10.1038/s42003-022-03219-w.
PMID: 35338238.
CrpP Is Not a Fluoroquinolone-Inactivating Enzyme →
Authors: Zubyk HL, Wright GD.
Reference: Antimicrob Agents Chemother.
DOI: 10.1128/AAC.00773-21.
PMID: 34001507.
ApmA Is a Unique Aminoglycoside Antibiotic Acetyltransferase That Inactivates Apramycin →
Authors: Bordeleau E, Stogios PJ, Evdokimova E, Koteva K, Savchenko A, Wright GD.
Reference: mBio
DOI: 10.1128/mBio.02705-20
PMID: 33563840
Identifying novel β-lactamase substrate activity through in silico prediction of antimicrobial resistance →
Authors: Tsang KK, Maguire F, Zubyk HL, Chou S, Edalatmand A, Wright GD, Beiko RG, McArthur AG.
Reference: Microb Genom
DOI: 10.1099/mgen.0.000500
PMID: 33416461
Antibiotic Resistance by Enzymatic Modification of Antibiotic Targets →
Authors: Schaenzer AJ and Wright GD
Reference: Trends Mol Med.
DOI: 10.1016/j.molmed.2020.05.001
PMID: 32493628
Antibiotic Dereplication Using the Antibiotic Resistance Platform →
Authors: Zubyk HL, Cox G and Wright GD
Reference: J Vis Exp.
DOI: 10.3791/60536
PMID: 31680676
The ADEP Biosynthetic Gene Cluster in Streptomyces hawaiiensis NRRL 15010 Reveals an Accessory clpP Gene as a Novel Antibiotic Resistance Factor →
Authors: Thomy D, Culp E, Adamek M, Cheng EY, Ziemert N, Wright GD, Sass P and Brötz-Oesterhelt H.
Reference: Appl Environ Microbiol.
DOI: 10.1128/AEM.01292-19
PMID: 31399403
Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis →
Authors: Stogios PJ, Cox G, Zubyk HL, Evdokimova E, Wawrzak Z, Wright GD, Savchenko A
Reference: ACS Chemical Biology 2018 13 (5), 1322-1332
DOI: 10.1021/acschembio.8b00116
PMID: 29631403
Rox, a Rifamycin Resistance Enzyme with an Unprecedented Mechanism of Action. →
Authors: Koteva K, Cox G, Kelso JK, Surette MD, Zubyk HL, Ejim L, Stogios P, Savchenko A, Sørensen, Wright GD
Reference: Cell Chemical Biology 2018 Jan 26. pii: S2451-9456(18)30031-X
DOI: 10.1016/j.chembiol.2018.01.009.
PMID: 29398560
Rifampin phosphotransferase is an unusual antibiotic resistance kinase →
Authors: Peter J Stogios, Georgina Cox, Peter Spanogiannopoulos, Monica C Pillon, Nicholas Waglechner, Tatiana Skarina, Kalinka Koteva, Alba Guarné, Alexei Savchenko, Gerard D Wright
Reference: Nat Commun. 2016 Apr 22;7:11343. doi: 10.1038/ncomms11343.
PMID: 27103605
Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins →
Authors: Andrew M King, Dustin T King, Shawn French, Eric Brouillette, Abdelhamid Asli, J Andrew N Alexander, Marija Vuckovic, Samarendra N Maiti, Thomas R Parr Jr, Eric D Brown, François Malouin, Natalie CJ Strynadka, Gerard D Wright
Reference: ACS Chem Biol. 2016 Apr 15;11(4):864-8. doi: 10.1021/acschembio.5b00944.
PMID: 26731698
Structural and molecular basis for resistance to aminoglycoside antibiotics by the adenylyltransferase ANT (2 ″)-Ia →
Authors: Georgina Cox, Peter J Stogios, Alexei Savchenko, Gerard D Wright
Reference: MBio. 2015 Jan 6;6(1). pii: e02180-14. doi: 10.1128/mBio.02180-14.
PMID: 25564464