Authors: Tushar Shakya, Peter J Stogios, Nicholas Waglechner, Elena Evdokimova, Linda Ejim, Jan E Blanchard, Andrew G McArthur, Alexei Savchenko, Gerard D Wright
Reference: Chem Biol. 2011 Dec 23;18(12):1591-601. doi: 10.1016/j.chembiol.2011.10.018.
PMID: 22195561
Palmitoyl‐DL‐carnitine is a multitarget inhibitor of Pseudomonas aeruginosa biofilm development →
Authors: Iwona B Wenderska, Matthew Chong, James McNulty, Gerard D Wright, Lori L Burrows
Reference: Chembiochem. 2011 Dec 16;12(18):2759-66. doi: 10.1002/cbic.201100500
PMID: 22045628
Microwave-assisted synthesis of N1-and C3-substituted pyrazolo [3, 4-d] pyrimidine libraries →
Authors: Nick Todorovic, Emelia Awuah, Tushar Shakya, Gerard D Wright, Alfredo Capretta
Reference: Tetrahedron Letters Volume 52, Issue 44, 2 November 2011, Pages 5761–5763
Antibiotic resistance is ancient →
Authors: Vanessa M D’Costa, Christine E King, Lindsay Kalan, Mariya Morar, Wilson WL Sung, Carsten Schwarz, Duane Froese, Grant Zazula, Fabrice Calmels, Regis Debruyne, G Brian Golding, Hendrik N Poinar, Gerard D Wright
Reference: Nature. 2011 Aug 31;477(7365):457-61. doi: 10.1038/nature10388.
PMID: 21881561
An ecological perspective of microbial secondary metabolism →
Authors: Jonathan O’Brien, Gerard D Wright
Reference: Curr Opin Biotechnol. 2011 Aug;22(4):552-8. doi: 10.1016/j.copbio.2011.03.010.
PMID: 21498065
β-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents →
Authors: Gianfranco De Pascale, Ishac Nazi, Paul HM Harrison, Gerard D Wright
Reference: J Antibiot (Tokyo). 2011 Jul;64(7):483-7. doi: 10.1038/ja.2011.37
PMID: 21522158
Structural basis for a new tetracycline resistance mechanism relying on the TetX monooxygenase →
Authors: G Volkers, GJ Palm, MS Weiss, GD Wright, W Hinrichs
Reference: FEBS Lett. 2011 Apr 6;585(7):1061-6. doi: 10.1016/j.febslet.2011.03.012.
PMID: 21402075
Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy →
Authors: Linda Ejim, Maya A Farha, Shannon B Falconer, Jan Wildenhain, Brian K Coombes, Mike Tyers, Eric D Brown, Gerard D Wright
Reference: Nat Chem Biol. 2011 Jun;7(6):348-50. doi: 10.1038/nchembio.559.
PMID: 21516114
The Antibiotic Resistome: Origins, Diversity, and Future Prospects →
Authors: Erin L Westman, Gerard D Wright
Reference: Handbook of Molecular Microbial Ecology II: Metagenomics in Different Habitats - Pages 165-174
Identification and characterization of new inhibitors of fungal homoserine kinase →
Authors: Gianfranco De Pascale, Emma J Griffiths, Tushar Shakya, Ishac Nazi, Gerard D Wright
Reference: Chembiochem. 2011 May 16;12(8):1179-82. doi: 10.1002/cbic.201100121.
PMID: 21538764
Antibiotic adjuvants: multicomponent anti-infective strategies →
Authors: Lindsay Kalan, Gerard D Wright
Reference: Expert Rev Mol Med. 2011 Feb 23;13:e5. doi: 10.1017/S1462399410001766.
PMID: 21342612
Molecular mechanisms of antibiotic resistance →
Authors: Gerard D Wright
Reference: Chem Commun (Camb). 2011 Apr 14;47(14):4055-61. doi: 10.1039/c0cc05111j.
PMID: 21286630
Receptor domains of two-component signal transduction systems →
Authors: Julie Perry, Kalinka Koteva, Gerard Wright
Reference: Mol Biosyst. 2011 May;7(5):1388-98. doi: 10.1039/c0mb00329h.
PMID: 21347487
Structure and function of APH (4)-Ia, a hygromycin B resistance enzyme →
Authors: Peter J Stogios, Tushar Shakya, Elena Evdokimova, Alexei Savchenko, Gerard D Wright
Reference: J Biol Chem. 2011 Jan 21;286(3):1966-75. doi: 10.1074/jbc.M110.194266.
PMID: 21084294
Cross‐species discovery of syncretic drug combinations that potentiate the antifungal fluconazole →
Authors: Michaela Spitzer, Emma Griffiths, Kim M Blakely, Jan Wildenhain, Linda Ejim, Laura Rossi, Gianfranco De Pascale, Jasna Curak, Eric Brown, Mike Tyers, Gerard D Wright
Reference: Mol Syst Biol. 2011 Jun 21;7:499. doi: 10.1038/msb.2011.31.
PMID: 21694716
Redox Mechanisms and Reactive Oxygen Species in Antibiotic Action and Resistance →
Authors: Inas J Radhi, Gerard D Wright
Reference: Bacterial Stress Responses, Second Edition, P. 461-471