Authors: Brian P Alcock, William Huynh, Romeo Chalil, Keaton W Smith, Amogelang R Raphenya, Mateusz A Wlodarski, Arman Edalatmand, Aaron Petkau, Sohaib A Syed, Kara K Tsang, Sheridan J C Baker, Mugdha Dave, Madeline C McCarthy, Karyn M Mukiri, Jalees A Nasir, Bahar Golbon, Hamna Imtiaz, Xingjian Jiang, Komal Kaur, Megan Kwong, Zi Cheng Liang, Keyu C Niu, Prabakar Shan, Jasmine Y J Yang, Kristen L Gray, Gemma R Hoad, Baofeng Jia, Timsy Bhando, Lindsey A Carfrae, Maya A Farha, Shawn French, Rodion Gordzevich, Kenneth Rachwalski, Megan M Tu, Emily Bordeleau, Damion Dooley, Emma Griffiths, Haley L Zubyk, Eric D Brown, Finlay Maguire, Robert G Beiko, William W L Hsiao, Fiona S L Brinkman, Gary Van Domselaar, Andrew G McArthur.
Reference: Nucleic Acids Research
DOI: 10.1093/nar/gkac920
PMID: 36263822
Lessons from assembling a microbial natural product and pre-fractionated extract library in an academic laboratory →
Authors: Cook M.A, Pallant D, Ejim L, Sutherland A.D, Wang X, Johnson J.W, McCusker S, Chen X, George A, Chou S, Koteva K, Wang W, Hobson C, Hackenberger D, Waglechner N, Ejim O, Campbell T, Medina R, MacNeil L.T, Wright G.D.
Reference: Journal of Industrial Microbiology and Biotechnology
DOI: 10.1093/jimb/kuad042
PMID: 38052426
Synthetic Biology Facilitates Semisynthetic Development of Type V Glycopeptide Antibiotics Targeting Vancomycin-Resistant Enterococcus →
Authors: Kalinka Koteva, Min Xu, Wenliang Wang, Aline A. Fiebig-Comyn, Michael A. Cook, Brian K. Coombes, and Gerard D. Wright
Reference: The Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c00633
PMID: 37315221
Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance →
Authors: Bordeleau E, Stogios PJ, Evdokimova E, Koteva K, Savchenko A, Wright GD.
Reference: Nature Chemical Biology
DOI: 10.1038/s41589-023-01483-3
PMID: 37973888
Angucyclinones rescue PhLOPSA antibiotic activity by inhibiting Cfr-dependent antibiotic resistance →
Authors: Schaenzer AJ, Hernandez AR, Tsai K, Hobson C, Fujimori DG, Wright GD.
Reference: ASM mBio.
DOI: 10.1128/mbio.01791-23
PMID: 38014974