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The Wright Lab

  • Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact

The genomic enzymology of antibiotic resistance →

Authors: Mariya Morar, Gerard D Wright
Reference: Annu Rev Genet. 2010;44:25-51. doi: 10.1146/annurev-genet-102209-163517.
PMID: 20822442

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tags: 2010
Wednesday 12.01.10
Posted by Wright Lab
 

Antibiotic resistance in the environment: a link to the clinic? →

Authors: Gerard D Wright
Reference: Curr Opin Microbiol. 2010 Oct;13(5):589-94. doi: 10.1016/j.mib.2010.08.005.
PMID: 20850375

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tags: 2010
Sunday 10.31.10
Posted by Wright Lab
 

Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: a model for the ClpX/ClpA-bound state of ClpP →

Authors: Dominic Him Shun Li, Yu Seon Chung, Melanie Gloyd, Ebenezer Joseph, Rodolfo Ghirlando, Gerard D Wright, Yi-Qiang Cheng, Michael R Maurizi, Alba Guarné, Joaquin Ortega
Reference: Chem Biol. 2010 Sep 24;17(9):959-69. doi: 10.1016/j.chembiol.2010.07.008.
PMID: 20851345 

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tags: 2010
Friday 09.24.10
Posted by Wright Lab
 

Q&A: Antibiotic resistance: where does it come from and what can we do about it? →

Authors: Gerard D Wright
Reference: BMC Biol. 2010 Sep 20;8:123. doi: 10.1186/1741-7007-8-123.
PMID: 20887638 

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tags: 2010
Monday 09.20.10
Posted by Wright Lab
 

The antibiotic resistome →

Authors: Gerard D Wright
Reference: Expert Opin Drug Discov. 2010 Aug;5(8):779-88. doi: 10.1517/17460441.2010.497535. 
PMID: 22827799

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tags: 2010
Sunday 08.01.10
Posted by Wright Lab
 

Antibiotic resistance by enzyme inactivation: from mechanisms to solutions →

Authors: Gianfranco De Pascale, Gerard D Wright
Reference: Chembiochem. 2010 Jul 5;11(10):1325-34. doi: 10.1002/cbic.201000067.
PMID: 20564281 

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tags: 2010
Monday 07.05.10
Posted by Wright Lab
 

A vancomycin photoprobe identifies the histidine kinase VanSsc as a vancomycin receptor →

Authors: Kalinka Koteva, Hee-Jeon Hong, Xiao Dong Wang, Ishac Nazi, Donald Hughes, Mike J Naldrett, Mark J Buttner, Gerard D Wright
Reference: Nat Chem Biol. 2010 May;6(5):327-9. doi: 10.1038/nchembio.350.
PMID: 20383152 

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tags: 2010, Kalinka Koteva
Saturday 05.01.10
Posted by Wright Lab
 

Nucleotide selectivity of antibiotic kinases →

Authors: Tushar Shakya, Gerard D Wright
Reference: Antimicrob Agents Chemother. 2010 May;54(5):1909-13. doi: 10.1128/AAC.01570-09
PMID: 20231391

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tags: 2010
Saturday 05.01.10
Posted by Wright Lab
 

Crystallization and preliminary X-ray crystallographic analysis of the tetracycline-degrading monooxygenase TetX2 from Bacteroides thetaiotaomicron →

Authors: Gesa Volkers, Linda Schuldt, Gottfried J Palm, Gerard D Wright, Winfried Hinrichs
Reference: Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 May 1;66(Pt 5):611-4. doi: 10.1107/S174430911001225X.
PMID: 20445272 

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tags: 2010
Saturday 05.01.10
Posted by Wright Lab
 

Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1 →

Authors: Nancy L McKenzie, Maulik Thaker, Kalinka Koteva, Donald W Hughes, Gerard D Wright, Justin R Nodwell
Reference: J Antibiot (Tokyo). 2010 Apr;63(4):177-82. doi: 10.1038/ja.2010.13. 
PMID: 20224601 

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tags: 2010, Kalinka Koteva
Thursday 04.01.10
Posted by Wright Lab
 

Antibiotics: inactive but not inert →

Authors: Gerard D Wright
Reference: Nat Chem Biol. 2010 Feb;6(2):85-6. doi: 10.1038/nchembio.299.
PMID: 20081820

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tags: 2010
Tuesday 02.02.10
Posted by Wright Lab
 

The tetracycline resistome →

Authors: Maulik Thaker, Peter Spanogiannopoulos, Gerard D Wright
Reference: Cell Mol Life Sci. 2010 Feb;67(3):419-31. doi: 10.1007/s00018-009-0172-6. 
PMID: 19862477

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tags: 2010
Monday 02.01.10
Posted by Wright Lab
 

Structural and kinetic characterization of the LPS biosynthetic enzyme d-α, β-d-heptose-1, 7-bisphosphate phosphatase (GmhB) from Escherichia coli

Authors: Patricia L Taylor, Seiji Sugiman-Marangos, Kun Zhang, Miguel A Valvano, Gerard D Wright, Murray S Junop
Reference: Biochemistry. 2010 Feb 9;49(5):1033-41. doi: 10.1021/bi901780j.
PMID: 20050699 

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tags: 2010
Thursday 01.14.10
Posted by Tomasz Czarny
 

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