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The Wright Lab

  • Welcome
  • Lab News
  • Team
    • Gerry Wright
    • The Lab
  • Research
    • An Overview
    • Antimicrobial Discovery
    • Antibiotic Resistance
  • Publications
  • Platforms
    • Wright Actinomycete Collection
    • Wright Clinical Collection
    • Antibiotic Resistance Platform
    • The Comprehensive Antibiotic Resistance Database
  • Articles
  • Contact
 
Min.png

Min Xu, Ph.D

Position: Postdoctoral Fellow

About:

Min joined the Lab in July 2017 after finishing his graduate study at Shanghai Jiao Tong University in the School of Life Sciences and Biotechnology. Min is a microbiologist and synethetic biologist specializing in natural products drug discovery and biosynthesis. In his spare time outside of the lab, Min likes playing basketball and listening to music.

 
Email
 

Research Interests:

Min's research interests focus on the utilization of synthetic biology to facilitate drug discovery and engineering antibiotics biosynthetic pathway for higher titer, and also on the deciphering of natural products biosynthetic logic. Now Min is working on the capturing and heterologous expression of a pluramycin-type antibiotic biosynthetic gene cluster, and also the metabolic engineering of its pathway for a better yield.

Publications:

Featured
Phylogeny-Informed Synthetic Biology Reveals Unprecedented Structural Novelty in Type V Glycopeptide Antibiotics
Apr 27, 2022
Phylogeny-Informed Synthetic Biology Reveals Unprecedented Structural Novelty in Type V Glycopeptide Antibiotics
Apr 27, 2022

Authors: Min Xu, Wenliang Wang, Nicholas Waglechner, Elizabeth J. Culp, Allison K. Guitor, and Gerard D. Wright.
Reference: ACS Central Science
DOI: 10.1021/acscentsci.1c01389.
PMID:

Apr 27, 2022
Glycopeptide antibiotic discovery in the genomic era
Dec 21, 2021
Glycopeptide antibiotic discovery in the genomic era
Dec 21, 2021

Authors: Xu M, Wang W, Wright GD.
Reference: Methods Enzymol.
DOI: 10.1016/bs.mie.2021.11.009. .
PMID: 35379441.

Dec 21, 2021
A non-reactive natural product precursor of the duocarmycin family has potent and selective antimalarial activity
Oct 23, 2021
A non-reactive natural product precursor of the duocarmycin family has potent and selective antimalarial activity
Oct 23, 2021

Authors: Alder A, Struck NS, Xu M, Johnson JW, Wang W, Pallant D, Cook MA, Rambow J, Lemcke S, Gilberger TW, Wright GD.
Reference: Cell Chem Biol.
DOI: 10.1016/j.chembiol.2021.10.005.
PMID: 34710358.

Oct 23, 2021
GPAHex-A synthetic biology platform for Type IV-V glycopeptide antibiotic production and discovery
Oct 16, 2020
GPAHex-A synthetic biology platform for Type IV-V glycopeptide antibiotic production and discovery
Oct 16, 2020

Authors: Xu M, Wang W, Waglechner N, Culp EJ, Guitor AK, Wright GD.
Reference: Nat Commun.
DOI: 10.1038/s41467-020-19138-5
PMID: 33067466

Oct 16, 2020
Heterologous expression-facilitated natural products’ discovery in actinomycetes
Nov 16, 2018
Heterologous expression-facilitated natural products’ discovery in actinomycetes
Nov 16, 2018

Authors: Xu M, Wright GD
Reference: J Ind Microbiol Biotechnol.
DOI: 10.1007/s10295-018-2097-2
PMID: 30446891

Nov 16, 2018

In the News:

Featured
Wright lab researchers develop new platform for antibiotic production and discovery
Oct 16, 2020
Wright lab researchers develop new platform for antibiotic production and discovery
Oct 16, 2020

Read about the recent publication here.

Oct 16, 2020
 
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