Caitlyn joined the Wright Lab in 2016 as a Ph.D. student after completing both a Bachelor of Science in Biochemistry and a Master of Science in Chemical Sciences at Laurentian University in Sudbury, Ontario.
Apart from Caitlyn’s love of science, she enjoys reading and spending time with family and friends. In addition, Caitlyn likes to roller blade, swim and play tennis.
Metallo-β-lactamases (MBLs) contribute largely to the problem of bacterial resistance to antibiotics as they have the capability of inactivating most β-lactam antibiotics. At the present time, there are no clinically approved inhibitors of MBLs. However, previous studies conducted in the Wright Lab have uncovered an effective inhibitor of two clinically relevant MBLs: NDM-1 and VIM-2. This inhibitor is known as aspergillomarasmine A (AMA), a natural product synthesized by the fungus Aspergillus versicolor. Caitlyn's research is focused on investigating unknown questions still surrounding AMA such as its biosynthesis in A. versicolor.
Authors: CM Rotondo and GD Wright
Reference: Current Opinion in Microbiology 2017 39: 96-105