Authors: Maulik N Thaker, Gerard D Wright
Reference: ACS Synth Biol. 2015 Mar 20;4(3):195-206. doi: 10.1021/sb300092n.
PMID: 23654249
First JA Medal goes to a paper on decalpenic acid →
Authors: Gerard D Wright, Minoru Yoshida
Reference: J Antibiot (Tokyo). 2012 Dec;65(12):591-2. doi: 10.1038/ja.2012.100.
PMID: 23258426
Bacterial inactivation of the anticancer drug doxorubicin →
Authors: Erin L Westman, Marc J Canova, Inas J Radhi, Kalinka Koteva, Inga Kireeva, Nicholas Waglechner, Gerard D Wright
Reference: Chem Biol. 2012 Oct 26;19(10):1255-64. doi: 10.1016/j.chembiol.2012.08.011.
PMID: 23102220
Inhibition of WTA synthesis blocks the cooperative action of PBPs and sensitizes MRSA to β-lactams →
Authors: Maya A Farha, Alexander Leung, Edward W Sewell, Michael A D’Elia, Sarah E Allison, Linda Ejim, Pedro M Pereira, Mariana G Pinho, Gerard D Wright, Eric D Brown
Reference: ACS Chem Biol. 2013 Jan 18;8(1):226-33. doi: 10.1021/cb300413m.
PMID: 23062620
Back to the future: a new ‘old’lead for tuberculosis →
Authors: Gerard D Wright
Reference: EMBO Mol Med. 2012 Oct;4(10):1029-31. doi: 10.1002/emmm.201201811.
PMID: 22987753
Characterization of a rifampin-inactivating glycosyltransferase from a screen of environmental actinomycetes →
Authors: Peter Spanogiannopoulos, Maulik Thaker, Kalinka Koteva, Nicholas Waglechner, Gerard D Wright
Reference: Antimicrob Agents Chemother. 2012 Oct;56(10):5061-9. doi: 10.1128/AAC.01166-12.
PMID: 22802246
The origins of antibiotic resistance →
Authors: Gerard D Wright
Reference: Antibiotic Resistance P. 13-30
Sulfonation of glycopeptide antibiotics by sulfotransferase StaL depends on conformational flexibility of aglycone scaffold →
Authors: Rong Shi, Christine Munger, Lindsay Kalan, Traian Sulea, Gerard D Wright, Miroslaw Cygler
Reference: Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11824-9. doi: 10.1073/pnas.1205377109.
PMID: 22753479
A forward chemical screen identifies antibiotic adjuvants in Escherichia coli →
Authors: Patricia L Taylor, Laura Rossi, Gianfranco De Pascale, Gerard D Wrigh
Reference: ACS Chem Biol. 2012 Sep 21;7(9):1547-55.
PMID: 22698393
Diversity of integron-and culture-associated antibiotic resistance genes in freshwater floc →
Authors: Christopher N Drudge, Amy VC Elliott, Janina M Plach, Linda J Ejim, Gerard D Wright, Ian G Droppo, Lesley A Warren
Reference: Appl Environ Microbiol. 2012 Jun;78(12):4367-72. doi: 10.1128/AEM.00405-12
PMID: 22467502
Antibiotic resistance is ancient: implications for drug discovery →
Authors: Gerard D Wright, Hendrik Poinar
Reference: Trends Microbiol. 2012 Apr;20(4):157-9. doi: 10.1016/j.tim.2012.01.002.
PMID: 22284896
Antibiotic resistance is prevalent in an isolated cave microbiome →
Authors: Kirandeep Bhullar, Nicholas Waglechner, Andrew Pawlowski, Kalinka Koteva, Eric D Banks, Michael D Johnston, Hazel A Barton, Gerard D Wright
Reference: PLoS One. 2012;7(4):e34953. doi: 10.1371/journal.pone.0034953.
PMID: 22509370
Determining the mode of action of bioactive compounds →
Authors: Marisa A Azad, Gerard D Wright
Reference: Bioorg Med Chem. 2012 Mar 15;20(6):1929-39. doi: 10.1016/j.bmc.2011.10.088.
PMID: 22300885
Small-molecule modulators of Listeria monocytogenes biofilm development →
Authors: Uyen T Nguyen, Iwona B Wenderska, Matthew A Chong, Kalinka Koteva, Gerard D Wright, Lori L Burrows
Reference: Appl Environ Microbiol. 2012 Mar;78(5):1454-65. doi: 10.1128/AEM.07227-11.
PMID: 22194285
Mechanism and diversity of the erythromycin esterase family of enzymes →
Authors: Mariya Morar, Kate Pengelly, Kalinka Koteva, Gerard D Wright
Reference: Biochemistry. 2012 Feb 28;51(8):1740-51. doi: 10.1021/bi201790u.
PMID: 22303981
Inactivation of the lipopeptide antibiotic daptomycin by hydrolytic mechanisms →
Authors: Vanessa M D'Costa, Tariq A Mukhtar, Tejal Patel, Kalinka Koteva, Nicholas Waglechner, Donald W Hughes, Gerard D Wright, Gianfranco De Pascale
Reference: Antimicrob Agents Chemother. 2012 Feb;56(2):757-64. doi: 10.1128/AAC.05441-11.
PMID: 22083474
Antibiotics: a new hope →
Authors: Gerard D Wright
Reference: Chem Biol. 2012 Jan 27;19(1):3-10. doi: 10.1016/j.chembiol.2011.10.019.
PMID: 22284349
Antibiotic resistome: A framework linking the clinic and the environment →
Authors: Gerard D Wright
Reference: Antimicrobial Resistance in the Environment
Biosynthetic gene cluster and antimicrobial activity of the elfamycin antibiotic factumycin →
Authors: MN Thaker, M García, K Koteva, N Waglechner, D Sorensen, R Medina, GD Wright
Reference: Med. Chem. Commun., 2012,3, 1020-1026 DOI: 10.1039/C2MD20038D