Haley joined the Wright lab in May 2016 to work on expanding the number of characterized resistance genes that make up the Antibiotic Resistance Platform (ARP). Since then, she has completed her fourth year undergraduate thesis in the lab which involved high-throughput screening for a natural product inhibitor of the tetracycline efflux pump, TetA. For her graduate studies, Haley is now investigating the mechanistic enzymology of β-amino acid synthesis in the peptide antibiotic edeine.
Haley's favourite things outside of the lab include coffee, Game of Thrones, and junk-food.
Haley's project involves using a combination of molecular and structural biology, biochemistry, and mechanistic enzymology to develop a better understanding of edeine biosynthesis.
Authors: Stogios PJ, Cox G, Zubyk HL, Evdokimova E, Wawrzak Z, Wright GD, Savchenko A
Reference: ACS Chemical Biology 2018 13 (5), 1322-1332
Authors: Koteva K, Cox G, Kelso JK, Surette MD, Zubyk HL, Ejim L, Stogios P, Savchenko A, Sørensen, Wright GD
Reference: Cell Chemical Biology 2018 Jan 26. pii: S2451-9456(18)30031-X